synthesis and pharmacological evaluation of thiazolidinediones



Sandra Mathison Really New Directions in Evaluation: Young Evaluators' Perspectives. New Directions for Evaluation, Number 131 Sandra Mathison Really New Directions in Evaluation: Young Evaluators' Perspectives. New Directions for Evaluation, Number 131 Новинка

Sandra Mathison Really New Directions in Evaluation: Young Evaluators' Perspectives. New Directions for Evaluation, Number 131

This issue of New Directions for Evaluation (NDE) marks a milestone: the 25th anniversary of the American Evaluation Association (AEA). NDE is an official publication of AEA and has been a crucial means for the Association to foster and promote the professionalization of evaluation through thematic discussions of theory and practice in evaluation. NDE was first published in 1978 under the name New Directions for Program Evaluation, although the title became New Directions for Evaluation in 1995 in acknowledgement of the broader scope of evaluation.
Dutwin Phyllis The ABCs of Evaluation. Timeless Techniques for Program and Project Managers Dutwin Phyllis The ABCs of Evaluation. Timeless Techniques for Program and Project Managers Новинка

Dutwin Phyllis The ABCs of Evaluation. Timeless Techniques for Program and Project Managers

Thoroughly revised and updated, the third edition of bestselling The ABCs of Evaluation offers an introduction to program evaluation. This comprehensive textbook covers topics such as stakeholder relationships, program design, data collection and analysis, reporting results, and other important steps in the evaluation process. The ABCs of Evaluation shows how to select participants for the evaluation and how to deal with multiple goals and objectives—including those of the organization, the staff, and the client. The authors illustrate the circumstances under which each evaluation model can be used, and offer tips on identifying data sources and collecting the data. This revision includes substantially increased coverage of theory, methodological approaches, the business of evaluation, the evaluator's role and responsibilities, RFPs and the grants process, logic models, data analysis, and writing the evaluation report. Also included are new cases and scenarios from various evaluation realms in social sciences, education, health, and human services. Throughout the book, charts, graphs, models, and lists help organize, extend, and facilitate the understanding of each evaluation concept. Praise for the Previous Edition of The ABCs of Evaluation «A useful general overview of the evaluation process. I would recommend it to program or project managers wanting to know more about the process of evaluation.» —American Journal of Evaluation «All students (and practitioners) should have this in their library; they will use it frequently.» —Patricia McGee, PhD, associate professor, University of Texas, San Antonio Companion Web site: www.josseybass.com/go/Boulmetis
Nielsen Steffen Bohni Performance Management and Evaluation. New Directions for Evaluation, Number 137 Nielsen Steffen Bohni Performance Management and Evaluation. New Directions for Evaluation, Number 137 Новинка

Nielsen Steffen Bohni Performance Management and Evaluation. New Directions for Evaluation, Number 137

This issue focuses on connections between performance management and evaluation, a contentious topic at the moment. It does so by placing evaluation and monitoring under the overarching concept of performance management, and then by investigating five complementarities between performance monitoring and measurement on the one hand, and evaluation on the other. These complementarities are: Sequential Informational Organizational Methodical Hierarchical. Several case studies discuss the uses and complementarities of evaluation and performance management in contexts including national and local governments and the work of government, philanthropic foundations, and a direct-service nonprofit agency. These cases illustrate the advantages and pitfalls in utilizing evaluative approaches within the context of performance management. This is the 137th volume of the Jossey-Bass quarterly report series New Directions for Evaluation, an official publication of the American Evaluation Association.
Dean Spaulding T. Program Evaluation in Practice. Core Concepts and Examples for Discussion and Analysis Dean Spaulding T. Program Evaluation in Practice. Core Concepts and Examples for Discussion and Analysis Новинка

Dean Spaulding T. Program Evaluation in Practice. Core Concepts and Examples for Discussion and Analysis

An updated guide to the core concepts of program evaluation This updated edition of Program Evaluation in Practice covers the core concepts of program evaluation and uses case studies to touch on real-world issues that arise when conducting an evaluation project. This important resource is filled with illustrative examples written in accessible terms and provides a wide variety of evaluation projects that can be used for discussion, analysis, and reflection. The book addresses foundations and theories of evaluation, tools and methods for collecting data, writing of reports, and the sharing of findings. The discussion questions and class activities at the end of each chapter are designed to help process the information in that chapter and to integrate the information from the other chapters, thus facilitating the learning process. As useful for students as it is for evaluators in training, Program Evaluation in Practice is a must-have text for those aspiring to be effective evaluators. Includes expanded discussion of basic theories and approaches to program evaluation Features a new chapter on objective-based evaluation and a new section on ethics in program evaluation Provides more detailed information and in-depth description for each case, including evaluation approaches, fresh references, new readings, and the new Joint Committee Standards for Evaluation
Stufflebeam Daniel L. Evaluation Theory, Models, and Applications Stufflebeam Daniel L. Evaluation Theory, Models, and Applications Новинка

Stufflebeam Daniel L. Evaluation Theory, Models, and Applications

The golden standard evaluation reference text Now in its second edition, Evaluation Theory, Models, and Applications is the vital text on evaluation models, perfect for classroom use as a textbook, and as a professional evaluation reference. The book begins with an overview of the evaluation field and program evaluation standards, and proceeds to cover the most widely used evaluation approaches. With new evaluation designs and the inclusion of the latest literature from the field, this Second Edition is an essential update for professionals and students who want to stay current. Understanding and choosing evaluation approaches is critical to many professions, and Evaluation Theory, Models, and Applications, Second Edition is the benchmark evaluation guide. Authors Daniel L. Stufflebeam and Chris L. S. Coryn, widely considered experts in the evaluation field, introduce and describe 23 program evaluation approaches, including, new to this edition, transformative evaluation, participatory evaluation, consumer feedback, and meta-analysis. Evaluation Theory, Models, and Applications, Second Edition facilitates the process of planning, conducting, and assessing program evaluations. The highlighted evaluation approaches include: Experimental and quasi-experimental design evaluations Daniel L. Stufflebeam's CIPP Model Michael Scriven's Consumer-Oriented Evaluation Michael Patton's Utilization-Focused Evaluation Robert Stake's Responsive/Stakeholder-Centered Evaluation Case Study Evaluation Key readings listed at the end of each chapter direct readers to the most important references for each topic. Learning objectives, review questions, student exercises, and instructor support materials complete the collection of tools. Choosing from evaluation approaches can be an overwhelming process, but Evaluation Theory, Models, and Applications, Second Edition updates the core evaluation concepts with the latest research, making this complex field accessible in just one book.
Lam Yulin Solid-Phase Organic Synthesis. Concepts, Strategies, and Applications Lam Yulin Solid-Phase Organic Synthesis. Concepts, Strategies, and Applications Новинка

Lam Yulin Solid-Phase Organic Synthesis. Concepts, Strategies, and Applications

10361.91 руб. Найти похожее
Presents both the fundamental concepts and the most recent applications in solid-phase organic synthesis With its emphasis on basic concepts, Solid-Phase Organic Synthesis guides readers through all the steps needed to design and perform successful solid-phase organic syntheses. The authors focus on the fundamentals of heterogeneous supports in the synthesis of organic molecules, explaining the use of a solid material to facilitate organic synthesis. This comprehensive text not only presents the fundamentals, but also reviews the most recent research findings and applications, offering readers everything needed to conduct their own state-of-the-art science experiments. Featuring chapters written by leading researchers in the field, Solid-Phase Organic Synthesis is divided into two parts: Part One, Concepts and Strategies, discusses the linker groups used to attach the synthesis substrate to the solid support, colorimetric tests to identify the presence of functional groups, combinatorial synthesis, and diversity-oriented synthesis. Readers will discover how solid-phase synthesis is currently used to facilitate the discovery of new molecular functionality. The final chapter discusses how using a support can change or increase reaction selectivity. Part Two, Applications, presents examples of the solid-phase synthesis of various classes of organic molecules. Chapters explore general asymmetric synthesis on a support, strategies for heterocyclic synthesis, and synthesis of radioactive organic molecules, dyes, dendrimers, and oligosaccharides. Each chapter ends with a set of conclusions that underscore the key concepts and methods. References in each chapter enable readers to investigate any topic in greater depth. With its presentation of basic concepts as well as recent findings and applications, Solid-Phase Organic Synthesis is the ideal starting point for students and researchers in organic, medicinal, and combinatorial chemistry who want to take full advantage of current solid-phase synthesis techniques.
Kenji Mori Chemical Synthesis of Hormones, Pheromones and Other Bioregulators Kenji Mori Chemical Synthesis of Hormones, Pheromones and Other Bioregulators Новинка

Kenji Mori Chemical Synthesis of Hormones, Pheromones and Other Bioregulators

11291.83 руб. Найти похожее
Many small molecules occur naturally as «messenger» chemicals which regulate the behaviour and functions of microbes, plants, insects and animals. Examples include hormones, pheromones, phytoalexins, and antifeedants. These biofunctional molecules are of great interest to researchers in helping develop our understanding of biological function and in the development of new drugs. However extracting them from nature can be prohibitively expensive, so there is great interest in devising methods of synthesising them from simple starting materials in the laboratory. Chemical Synthesis of Hormones, Pheromones and Other Bioregulators is an introduction to the techniques and strategies for the synthesis of biofunctional small molecules. Topics include: what are biofunctional molecules? why must biofunctional molecules be synthesized? how can we synthesize biofunctional molecules? the synthesis of phytohormones, phytoalexins and other biofunctional molecules of plant origin the synthesis of insect juvenile hormones and antifeedants the synthesis of pheromones and the significance of chirality in pheromone science the synthesis of microbial hormones and pheromones, antibiotics, and other biofunctional molecules of microbial origin the synthesis of marine antifeedants and medicinal candidates a synthetic examination of incorrectly proposed structures of biomolecules reflections on science as a human endeavor Drawing on a career of almost 50 years researching and teaching this subject, Kenji Mori's Chemical Synthesis of Hormones, Pheromones and Other Bioregulators is a must-have textbook for students and researchers of organic synthesis and natural products, and a stimulating and inspiring account of a distinguished chemical career.
Johnson Douglas S. Modern Drug Synthesis Johnson Douglas S. Modern Drug Synthesis Новинка

Johnson Douglas S. Modern Drug Synthesis

Following Contemporary Drug Synthesis and The Art of Drug Synthesis (Wiley, 2004 and 2007), two well-received works, is this new book that demystifies the process of modern drug discovery for practitioners and students. An enhanced introduction covers areas such as background, pharmacology, SAR, PK/PD, efficacy, and safety. Focusing on the advantages of process synthesis versus the discovery synthetic route, Modern Drug Synthesis features authoritative coverage by distinguished editors and authors (some chapter authors are the actual inventor of the drug) of twenty different drug molecules.
Baron Michelle E. Internal Evaluation in the 21st Century. New Directions for Evaluation, Number 132 Baron Michelle E. Internal Evaluation in the 21st Century. New Directions for Evaluation, Number 132 Новинка

Baron Michelle E. Internal Evaluation in the 21st Century. New Directions for Evaluation, Number 132

Nowadays, a considerable amount of evaluation work is implemented internally—both nationally and across the world. As such, it is exceedingly important for evaluators and organizations to be aware of the issues in designing and implementing internal evaluation to realize its potential for enhancing organizational growth, competitive advantage, and social impact. This issue includes perspectives on internal evaluation from experienced evaluation practitioners from different fields and organizations who share theoretical and practical examples and case studies in promoting and conducting internal evaluation. The chapters: Highlight societal and organizational changes that have shaped the current trends in internal evaluation Discuss foundational issues in internal evaluation Provide rich illustrations of internal evaluation practice in different settings with diverse foci (customer-driven vision and a results-based orientation for evaluation, accountability and development, and building evaluation capacity). This is the 132nd volume of the Jossey-Bass quarterly report series New Directions for Evaluation, an official publication of the American Evaluation Association.
Moseley James L. Handbook of Improving Performance in the Workplace, Measurement and Evaluation Moseley James L. Handbook of Improving Performance in the Workplace, Measurement and Evaluation Новинка

Moseley James L. Handbook of Improving Performance in the Workplace, Measurement and Evaluation

12484.11 руб. Найти похожее
HANDBOOK of IMPROVING PERFORMANCE IN THE WORKPLACE Volume 3: Measurement and Evaluation Volume Three of the Handbook of Improving Performance in the Workplace focuses on Measurement and Evaluation and represents an invaluable addition to the literature that supports the field and practice of Instructional Systems Design. With contributions from leading national scholars and practitioners, this volume is filled with information on time-tested theories, leading-edge research, developments, and applications and provides a comprehensive review of the most pertinent information available on critical topics, including: Measuring and Evaluating Learning and Performance, Designing Evaluation, Qualitative and Quantitative Performance Measurements, Evidence-based Performance Measurements, Analyzing Data, Planning Performance Measurement and Evaluation, Strategies for Implementation, Business Evaluation Strategy, Measurement and Evaluation in Non-Profit Sectors, among many others. It also contains illustrative case studies and performance support tools. Sponsored by International Society for Performance Improvement (ISPI), the Handbook of Improving Performance in the Workplace, three-volume reference, covers three core areas of interest including Instructional Design and Training Delivery, Selecting and Implementing Performance Interventions, and Measurement and Evaluation.
Laurie Starkey S. Introduction to Strategies for Organic Synthesis Laurie Starkey S. Introduction to Strategies for Organic Synthesis Новинка

Laurie Starkey S. Introduction to Strategies for Organic Synthesis

The stepping-stone text for students with a preliminary knowledge of organic chemistry looking to move into organic synthesis research and graduate-level coursework Organic synthesis is an advanced but important field of organic chemistry, however resources for advanced undergraduates and graduate students moving from introductory organic chemistry courses to organic synthesis research are scarce. Introduction to Strategies for Organic Synthesis is designed to fill this void, teaching practical skills for making logical retrosynthetic disconnections, while reviewing basic organic transformations, reactions, and reactivities. Divided into seven parts that include sections on Retrosynthesis and Protective Groups; Overview of Organic Transformations; Synthesis of Monofunctional Target Molecules; Synthesis of Target Molecules with Two Functional Groups; Synthesis of Aromatic Target Molecules; Synthesis of Compounds Containing Rings; and Predicting and Controlling Stereochemistry, the book covers everything students need to successfully perform retrosynthetic analyses of target molecule synthesis. Starting with a review of functional group transformations, reagents, and reaction mechanisms, the book demonstrates how to plan a synthesis, explaining functional group analysis and strategic disconnections. Incorporating a review of the organic reactions covered, it also demonstrates each reaction from a synthetic chemist's point of view, to provide students with a clearer understanding of how retrosynthetic disconnections are made. Including detailed solutions to over 300 problems, worked-through examples and end-of-chapter comprehension problems, Introduction to Strategies for Organic Synthesis serves as a stepping stone for students with an introductory knowledge of organic chemistry looking to progress to more advanced synthetic concepts and methodologies.
Obaidat Mohammed S. Fundamentals of Performance Evaluation of Computer and Telecommunications Systems Obaidat Mohammed S. Fundamentals of Performance Evaluation of Computer and Telecommunications Systems Новинка

Obaidat Mohammed S. Fundamentals of Performance Evaluation of Computer and Telecommunications Systems

The only singular, all-encompassing textbook on state-of-the-art technical performance evaluation Fundamentals of Performance Evaluation of Computer and Telecommunication Systems uniquely presents all techniques of performance evaluation of computers systems, communication networks, and telecommunications in a balanced manner. Written by the renowned Professor Mohammad S. Obaidat and his coauthor Professor Noureddine Boudriga, it is also the only resource to treat computer and telecommunication systems as inseparable issues. The authors explain the basic concepts of performance evaluation, applications, performance evaluation metrics, workload types, benchmarking, and characterization of workload. This is followed by a review of the basics of probability theory, and then, the main techniques for performance evaluation—namely measurement, simulation, and analytic modeling—with case studies and examples. Contains the practical and applicable knowledge necessary for a successful performance evaluation in a balanced approach Reviews measurement tools, benchmark programs, design of experiments, traffic models, basics of queueing theory, and operational and mean value analysis Covers the techniques for validation and verification of simulation as well as random number generation, random variate generation, and testing with examples Features numerous examples and case studies, as well as exercises and problems for use as homework or programming assignments Fundamentals of Performance Evaluation of Computer and Telecommunication Systems is an ideal textbook for graduate students in computer science, electrical engineering, computer engineering, and information sciences, technology, and systems. It is also an excellent reference for practicing engineers and scientists.
Giacalone Francesco Catalytic Methods in Asymmetric Synthesis. Advanced Materials, Techniques, and Applications Giacalone Francesco Catalytic Methods in Asymmetric Synthesis. Advanced Materials, Techniques, and Applications Новинка

Giacalone Francesco Catalytic Methods in Asymmetric Synthesis. Advanced Materials, Techniques, and Applications

11354.93 руб. Найти похожее
This book covers advances in the methods of catalytic asymmetric synthesis and their applications. Coverage moves from new materials and technologies to homogeneous metal-free catalysts and homogeneous metal catalysts. The applications of several methodologies for the synthesis of biologically active molecules are discussed. Part I addresses recent advances in new materials and technologies such as supported catalysts, supports, self-supported catalysts, chiral ionic liquids, supercritical fluids, flow reactors and microwaves related to asymmetric catalysis. Part II covers advances and milestones in organocatalytic, enzymatic and metal-based mediated asymmetric synthesis, including applications for the synthesis of biologically active molecules. Written by leading international experts, this book consists of 16 chapters with 2000 References and illustrations of 560 schemes and figures.
Pher Andersson G. Innovative Catalysis in Organic Synthesis. Oxidation, Hydrogenation, and C-X Bond Forming Reactions Pher Andersson G. Innovative Catalysis in Organic Synthesis. Oxidation, Hydrogenation, and C-X Bond Forming Reactions Новинка

Pher Andersson G. Innovative Catalysis in Organic Synthesis. Oxidation, Hydrogenation, and C-X Bond Forming Reactions

C-H, C-O, C-C, and C-Heteroatom bond forming processes by using metal-ligand approaches for the synthesis of organic compounds of biological, pharmacological and organic nanotechnological utility are the key areas addressed in this book. Authored by a European team of leaders in the field, it brings together innovative approaches for a variety of catalysis reactions and processes frequently applied in organic synthesis into a handy reference work. It covers all major types of catalysis, including homogeneous, heterogeneous, and organocatalysis, as well as mechanistic and computational studies. Special attention is paid to the improvements in efficiency and sustainability of important catalytic processes, such as selective oxidations, hydrogenation, and cross-coupling reactions, and to their utilization in industry. The result is a valuable resource for advanced researchers in both academia and industry, as well as graduate students in organic chemistry aiming for chemo-, regio- or stereoselective synthesis of organic compounds by using novel catalytic systems.
Montrosse-Moorhead Bianca Revisiting Truth, Beauty,and Justice: Evaluating With Validity in the 21st Century. New Directions for Evaluation, Number 142 Montrosse-Moorhead Bianca Revisiting Truth, Beauty,and Justice: Evaluating With Validity in the 21st Century. New Directions for Evaluation, Number 142 Новинка

Montrosse-Moorhead Bianca Revisiting Truth, Beauty,and Justice: Evaluating With Validity in the 21st Century. New Directions for Evaluation, Number 142

This issue discusses ways of constructing, organizing, and managing arguments for evaluation. Not focued solely on the logic of evaluation or predictive validity, it discusses the various elements needed to construct evaluation arguments that are compelling and influential by virtue of the truth, beauty, and justice they express. Through exposition, original research, critical reflection, and application to case examples, the authors present tools, perspectives, and guides to help evaluators navigate the complex contexts of evaluation in the 21st century. This is the 142nd issue in the New Directions for Evaluation series from Jossey-Bass. It is an official publication of the American Evaluation Association.
Nahar Chowdhury Lutfun Steroid Dimers. Chemistry and Applications in Drug Design and Delivery Nahar Chowdhury Lutfun Steroid Dimers. Chemistry and Applications in Drug Design and Delivery Новинка

Nahar Chowdhury Lutfun Steroid Dimers. Chemistry and Applications in Drug Design and Delivery

12753.12 руб. Найти похожее
Steroid dimers are an important group of compounds produced by various marine organisms, and also synthesized in the laboratories. This group of compounds possesses various pharmacological and biological properties, and can also be used to create “molecular umbrellas” for drug delivery. Steroid Dimers: Chemistry and Applications in Drug Design and Delivery provides an up-to-date overview on the chemistry and applications of steroid dimers of natural and synthetic origins. The book includes easy-to-follow synthetic protocols for various classes of important dimeric steroids, source details, valuable spectroscopic data and depiction of unique structural features of natural steroidal dimers, and the Structure-Activity-Relationships (SARs) of some pharmacologically active dimeric steroids. Topics covered include: introduction to steroid dimers synthesis and chemistry of noncyclic and cyclic steroid dimers naturally occurring steroid dimers – cephalostatins, ritterazines and crellastatins biological and pharmacological functions of steroid dimers and their application in drug design and discovery steroid dimers as “molecular umbrellas” for drug delivery Steroid Dimers: Chemistry and Applications in Drug Design and Delivery is an essential guide to this important class of natural and synthetic compounds for researchers and students of natural products chemistry and biochemistry, synthetic organic and medicinal chemistry, and drug design, discovery and delivery.
Kushner Saville Evaluation Voices from Latin America. New Directions for Evaluation, Number 134 Kushner Saville Evaluation Voices from Latin America. New Directions for Evaluation, Number 134 Новинка

Kushner Saville Evaluation Voices from Latin America. New Directions for Evaluation, Number 134

Hear from evaluation practitioners throughout Latin America. In this region program evaluation is an emergent practice, one that is shaped by distinctive geopolitical and social contexts and has its own intellectual biography. Through a selection of writings and cases this issue provides a window on program evaluation in this region. The articles indicate a range of experiences and concerns that respond to the countries’ unique histories and cultures. Articles by evaluators from Argentina, Brazil, Chile, Colombia, Costa Rica, and Peru illustrate new directions and are grouped around the following themes: Strategic use of evaluation in public policies and active citizenship Innovative project evaluation examples Evaluation capacity building and institutionalization. The widespread development of participatory or actor-oriented approaches, based on qualitative methodologies that have a particularly Latin American stamp, are emphasized in this issue. This is the 134th volume of the Jossey-Bass quarterly report series New Directions for Evaluation, an official publication of the American Evaluation Association.
Cossy Janine Modern Tools for the Synthesis of Complex Bioactive Molecules Cossy Janine Modern Tools for the Synthesis of Complex Bioactive Molecules Новинка

Cossy Janine Modern Tools for the Synthesis of Complex Bioactive Molecules

10956.39 руб. Найти похожее
All the latest tools needed to plan and perform the synthesis of complex bioactive molecules Focusing on organic, organometallic, and bio-oriented processes, this book explores the impact and use of the latest synthetic tools for the synthesis of complex biologically active compounds. Readers will discover step by step how these synthetic tools have provided new, elegant solutions to many synthetic puzzles. Moreover, they will discover innovative methods that make it possible to control the exact connectivity of atoms within a molecule in order to set precise three-dimensional arrangements. Modern Tools for the Synthesis of Complex Bioactive Molecules features sixteen chapters, each one written by one or more leading experts in organic synthesis from around the world. It covers a broad range of topics that enable readers to take advantage of the latest methods for synthesizing complex molecules, including: Modern catalysis, emphasizing key transformations such as C-H functionalizations, cross-couplings, gold-catalyzed reactions, metathesis-based syntheses, and asymmetric organocatalysis Eco-compatible transformations, including rearrangements and domino reactions Tools for the synthesis of carbohydrates and alkaloids New techniques, including the use of fluorous tags and engineered biosynthesis The last two chapters explore target- and diversity-oriented organic synthesis as well as the use of DNA-based asymmetric catalysis, which are all promising tools for the successful synthesis of complex bioactive molecules. Modern Tools for the Synthesis of Complex Bioactive Molecules is ideal for students and researchers who need to plan and perform the synthesis of complex molecules as efficiently as possible. The book's expert advice will help these readers quickly resolve a broad range of problems that can arise in organic syntheses.
Cousins J. Bradley Organizational Capacity to Do and Use Evaluation. New Directions for Evaluation, Number 141 Cousins J. Bradley Organizational Capacity to Do and Use Evaluation. New Directions for Evaluation, Number 141 Новинка

Cousins J. Bradley Organizational Capacity to Do and Use Evaluation. New Directions for Evaluation, Number 141

Gain a greater understanding of organizational capacity to do and use evaluation and implications for evaluation capacity building (ECB). This volume is unique in that it represents a multiple case study of eight organizations that were committed to ECB. It: Situates the study in terms of ECB theory and research Delineates a conceptual framework Presents case profile reports and the results of a cross-case analysis. Discusses findings in terms of implications for research, theory, and practice. This is the 141st issue in the New Directions for Evaluation series from Jossey-Bass. It is an official publication of the American Evaluation Association.
Dominique Estampe Supply Chain Performance and Evaluation Models Dominique Estampe Supply Chain Performance and Evaluation Models Новинка

Dominique Estampe Supply Chain Performance and Evaluation Models

This book presents the different models of supply chain performance evaluation for global supply chains. It describes why it is necessary to evaluate global performance both to assess the contribution of the supply chain to achieve the goals of creating value throughout the chain and also to meet customer requirements in terms of time, responsiveness and reliability. The author provides an understanding of how evaluation models are chosen according to criteria including the level of maturity of the organization, the level of decision-making and the level of value creation desired.
Piet W. N. M. van Leeuwen Phosphorus(III) Ligands in Homogeneous Catalysis. Design and Synthesis Piet W. N. M. van Leeuwen Phosphorus(III) Ligands in Homogeneous Catalysis. Design and Synthesis Новинка

Piet W. N. M. van Leeuwen Phosphorus(III) Ligands in Homogeneous Catalysis. Design and Synthesis

13417.35 руб. Найти похожее
Over the last 60 years the increasing knowledge of transition metal chemistry has resulted in an enormous advance of homogeneous catalysis as an essential tool in both academic and industrial fields. Remarkably, phosphorus(III) donor ligands have played an important role in several of the acknowledged catalytic reactions. The positive effects of phosphine ligands in transition metal homogeneous catalysis have contributed largely to the evolution of the field into an indispensable tool in organic synthesis and the industrial production of chemicals. This book aims to address the design and synthesis of a comprehensive compilation of P(III) ligands for homogeneous catalysis. It not only focuses on the well-known traditional ligands that have been explored by catalysis researchers, but also includes promising ligand types that have traditionally been ignored mainly because of their challenging synthesis. Topics covered include ligand effects in homogeneous catalysis and rational catalyst design, P-stereogenic ligands, calixarenes, supramolecular approaches, solid phase synthesis, biological approaches, and solubility and separation. Ligand families covered in this book include phosphine, diphosphine, phosphite, diphosphite, phosphoramidite, phosphonite, phosphinite, phosphole, phosphinine, phosphinidenene, phosphaalkenes, phosphaalkynes, P-chiral ligands, and cage ligands. Each ligand class is accompanied by detailed and reliable synthetic procedures. Often the rate limiting step in the application of ligands in catalysis is the synthesis of the ligands themselves, which can often be very challenging and time consuming. This book will provide helpful advice as to the accessibility of ligands as well as their synthesis, thereby allowing researchers to make a more informed choice. Phosphorus(III) Ligands in Homogeneous Catalysis: Design and Synthesis is an essential overview of this important class of catalysts for academic and industrial researchers working in catalyst development, organometallic and synthetic chemistry.
V. Nenajdenko Isocyanide Chemistry. Applications in Synthesis and Material Science V. Nenajdenko Isocyanide Chemistry. Applications in Synthesis and Material Science Новинка

V. Nenajdenko Isocyanide Chemistry. Applications in Synthesis and Material Science

The efficacy of isocyanide reactions in the synthesis of natural or naturallike products has resulted in a renaissance of isocyanide chemistry. Now isocyanides are widely used in different branches of organic, inorganic, coordination, combinatorial and medicinal chemistry. This invaluable reference is the only book to cover the topic in such depth, presenting all aspects of synthetic isonitrile chemistry. The highly experienced and internationally renowned editor has brought together an equally distinguished team of authors who cover multicomponent reactions, isonitriles in total synthesis, isonitriles in polymer chemistry and much more.
Shinichi Itsuno Polymeric Chiral Catalyst Design and Chiral Polymer Synthesis Shinichi Itsuno Polymeric Chiral Catalyst Design and Chiral Polymer Synthesis Новинка

Shinichi Itsuno Polymeric Chiral Catalyst Design and Chiral Polymer Synthesis

11022.81 руб. Найти похожее
This book reviews chiral polymer synthesis and its application to asymmetric catalysis. It features the design and use of polymer-immobilized catalysts and methods for their design and synthesis. Chapters cover peptide-catalyzed and enantioselective synthesis, optically-active polymers, and continuous flow processes. It collects recent advances in an important field of polymer and organic chemistry, with leading researchers explaining applications in academic and industry R & D.
Gongkang Fu Bridge Design and Evaluation. LRFD and LRFR Gongkang Fu Bridge Design and Evaluation. LRFD and LRFR Новинка

Gongkang Fu Bridge Design and Evaluation. LRFD and LRFR

A succinct, real-world approach to complete bridge system design and evaluation Load and Resistance Factor Design (LRFD) and Load and Resistance Factor Rating (LRFR) are design and evaluation methods that have replaced or offered alternatives to other traditional methods as the new standards for designing and load-rating U.S. highway bridges. Bridge Design and Evaluation covers complete bridge systems (substructure and superstructure) in one succinct, manageable package. It presents real-world bridge examples demonstrating both their design and evaluation using LRFD and LRFR. Designed for a 3- to 4-credit undergraduate or graduate-level course, it presents the fundamentals of the topic without expanding needlessly into advanced or specialized topics. Important features include: Exclusive focus on LRFD and LRFR Hundreds of photographs and figures of real bridges to connect the theoretical with the practical Design and evaluation examples from real bridges including actual bridge plans and drawings and design methodologies Numerous exercise problems Specific design for a 3- to 4-credit course at the undergraduate or graduate level The only bridge engineering textbook to cover the important topics of bridge evaluation and rating Bridge Design and Evaluation is the most up-to-date and inclusive introduction available for students in civil engineering specializing in structural and transportation engineering.
Anbanandam Parthiban Synthesis and Applications of Copolymers Anbanandam Parthiban Synthesis and Applications of Copolymers Новинка

Anbanandam Parthiban Synthesis and Applications of Copolymers

Understanding the reactivity of monomers is crucial in creating copolymers and determining the outcome of copolymerization. Covering the fundamental aspects of polymerization, Synthesis and Applications of Copolymers explores the reactivity of monomers and reaction conditions that ensure that the newly formed polymeric materials exhibit desired properties. Referencing a wide-range of disciplines, the book provides researchers, students, and scientists with the preparation of a diverse variety of copolymers and their recent developments, with a particular focus on copolymerization, crystallization, and techniques like nanoimprinting and micropatterning.
Wyatt Paul Workbook for Organic Synthesis: The Disconnection Approach Wyatt Paul Workbook for Organic Synthesis: The Disconnection Approach Новинка

Wyatt Paul Workbook for Organic Synthesis: The Disconnection Approach

One approach to organic synthesis is retrosynthetic analysis. With this approach chemists start with the structures of their target molecules and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. This “disconnection” approach to synthesis is now a fundamental part of every organic synthesis course. Workbook for Organic Synthesis: The Disconnection Approach, 2nd Edition This workbook provides a comprehensive graded set of problems to illustrate and develop the themes of each of the chapters in the textbook Organic Synthesis: The Disconnection Approach, 2nd Edition. Each problem is followed by a fully explained solution and discussion. The examples extend the student’s experience of the types of molecules being synthesised by organic chemists, and the strategies they employ to control their syntheses. By working through these examples students will develop their skills in analysing synthetic challenges, and build a toolkit of strategies for planning new syntheses. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. Together the workbook and textbook provide a complete course in retrosynthetic analysis. Organic Synthesis: The Disconnection Approach, 2nd Edition There are forty chapters in Organic Synthesis: The Disconnection Approach, 2nd Edition: those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specifically designed for difficult problems. In its second edition updated examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel, Organic Synthesis: Strategy and Control. Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry. Workbook for Organic Synthesis: The Disconnection Approach, 2nd edition, combined with the main textbook, provides a full course in retrosynthetic analysis for chemistry and biochemistry students, and a refresher course for organic chemists working in industry and academia.
Andrushko Natalia Stereoselective Synthesis of Drugs and Natural Products Andrushko Natalia Stereoselective Synthesis of Drugs and Natural Products Новинка

Andrushko Natalia Stereoselective Synthesis of Drugs and Natural Products

34871.81 руб. Найти похожее
Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.
Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Building Blocks, Catalysis and Coupling Chemistry Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Building Blocks, Catalysis and Coupling Chemistry Новинка

Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Building Blocks, Catalysis and Coupling Chemistry

15210.75 руб. Найти похожее
This is the third of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international «who's who» in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures. The 5 volumes cover the following topics: Volume 1: Origins and Synthesis of Amino Acids Volume 2: Modified Amino Acids, Organocatalysis and Enzymes Volume 3: Building Blocks, Catalysis and Coupling Chemistry Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Volume 5: Analysis and Function of Amino Acids and Peptides This third volume in the series presents an in depth account of recent developments in the (bio-)synthesis of amino acids and peptides. Divided into two parts, the first section deals with amino acids as building blocks, including the generation of alpha-amino acids, beta-lactams, and heterocycles. The second section is devoted to the synthesis of peptides, with the focus on solid phase synthesis. However, solution phase peptide synthesis is covered as well, as are topics such as coupling reagents, chemical ligation, peptide purification and automation. Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage. Further information about the 5 Volume Set and purchasing details can be viewed here.
Ari M. P. Koskinen Asymmetric Synthesis of Natural Products Ari M. P. Koskinen Asymmetric Synthesis of Natural Products Новинка

Ari M. P. Koskinen Asymmetric Synthesis of Natural Products

11291.83 руб. Найти похожее
Asymmetric Synthesis of Natural Products, 2nd Edition introduces students to this rapidly growing field of organic chemistry. The initial chapters present the foundations of asymmetric synthesis, including the theory and applications of individual asymmetric reactions. This is followed by chapters on each of the major individual classes of natural products; their structures, biosynthesis and interrelationships as well as examples of asymmetric syntheses and the practical value of these compounds. Natural product classes covered include carbohydrates, amino acids, peptides, proteins, nucleosides, nucleotides, nucleic acids, polyketides, isoprenoids, shikamic acid derivatives and alkaloids. For this second edition the text has been thoroughly updated and expanded, and includes new discussions and examples covering atom and redox economies, practical aspects and environmental awareness. Organocatalysis has emerged completely in the last ten years, and has been fully integrated into this new edition.
Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Новинка

Andrew Hughes B. Amino Acids, Peptides and Proteins in Organic Chemistry, Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis

15210.75 руб. Найти похожее
This is the fourth of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international «who's who» in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures. The 5 volumes cover the following topics: Volume 1: Origins and Synthesis of Amino Acids Volume 2: Modified Amino Acids, Organocatalysis and Enzymes Volume 3: Building Blocks, Catalysis and Coupling Chemistry Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Volume 5: Analysis and Function of Amino Acids and Peptides The fourth volume in this series is structured in three main sections. The first section is about protection reactions and amino acid based peptidomimetics. The second, and most extensive, part is devoted to the medicinal chemistry of amino acids. It includes, among others, the chemistry of alpha- and beta amino acids, peptide drugs, and advances in N- and O-glycopeptide synthesis. The final part deals with amino acids in combinatorial synthesis. Methods, such as phage display, library peptide synthesis, and computational design are described. Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage. Further information about the 5 Volume Set and purchasing details can be viewed here.
Nicolais Luigi Nanocomposites. In Situ Synthesis of Polymer-Embedded Nanostructures Nicolais Luigi Nanocomposites. In Situ Synthesis of Polymer-Embedded Nanostructures Новинка

Nicolais Luigi Nanocomposites. In Situ Synthesis of Polymer-Embedded Nanostructures

A Step-by-step guide to the synthesis and characterization of metal-polymer nanocomposites Polymer nanocomposites, polymers that are reinforced with nano-sized particles, provide enhanced mechanical, thermal, electrical, and barrier properties. Continued research and development of new polymer nanocomposites promises to provide enhanced materials to a broad range of industries, such as plastics, aerospace, automotive, electronics, packaging, and biomedical devices. Structured as a practical laboratory manual, this book enables readers to expertly synthesize and characterize metal-polymer nanocomposites by clearly setting forth the principles and techniques. Nanocomposites: In Situ Synthesis of Polymer-Embedded Nanostructures features contributions from an international team of materials science and nanotechnology experts. Chapters reflect the authors' critical review of the literature as well as their own laboratory experience working with polymer nanocomposites. The book begins with a detailed introduction to the science, properties, and applications of metal-polymer nanocomposites. Next, it covers such topics as: Morphological and topological concepts Phase separation and nanoparticle aggregation Methods for the synthesis of nanocomposites Morphological control Characterization techniques and data analysis methods Toxicity considerations High-resolution images of metal nanoparticles, created by transmission electron microscopy, are provided throughout the book. There are also plenty of process schemes and detailed drawings, helping readers better understand how to synthesize, characterize, and use these composite materials. A bibliography at the end of each chapter provides a gateway to original research papers and reviews in the field. With its focus on the practical steps of synthesis and characterization, Nanocomposites: In Situ Synthesis of Polymer-Embedded Nanostructures is recommended for both students and practitioners in nanotechnology, polymer science, and materials science and engineering.
Zhang Wei Green Techniques for Organic Synthesis and Medicinal Chemistry Zhang Wei Green Techniques for Organic Synthesis and Medicinal Chemistry Новинка

Zhang Wei Green Techniques for Organic Synthesis and Medicinal Chemistry

14214.42 руб. Найти похожее
An updated overview of the rapidly developing field of green engineering techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.
Horikoshi Satoshi Microwaves in Nanoparticle Synthesis. Fundamentals and Applications Horikoshi Satoshi Microwaves in Nanoparticle Synthesis. Fundamentals and Applications Новинка

Horikoshi Satoshi Microwaves in Nanoparticle Synthesis. Fundamentals and Applications

13018.81 руб. Найти похожее
For the first time, this comprehensive handbook presents the emerging field of microwave technology for the synthesis of nanoparticles. Divided into three parts–fundamentals, methods, and applications–it covers topics including microwave theory, scale-up, microwave plasma synthesis, characterization, and more. This offers both an important volume for academic researchers, and a resource for those in industry exploring the applications of nanoparticles in semiconductors, electronics, catalysis, sensors, and more.
Vikas Mittal Renewable Polymers. Synthesis, Processing, and Technology Vikas Mittal Renewable Polymers. Synthesis, Processing, and Technology Новинка

Vikas Mittal Renewable Polymers. Synthesis, Processing, and Technology

12952.39 руб. Найти похожее
Presents the synthesis, technology and processing details of a large range of polymers derived from renewable resources It has been a long-term desire to replace polymers from fossil fuels with the more environmentally friendly polymers generated from renewable resources. Now, with the recent advancements in synthesis technologies and the finding of new functional monomers, research in this field has shown strong potential in generating better property polymers from renewable resources. A text describing these advances in synthesis, processing, and technology of such polymers not only provides the state-of-the-art information to researchers, but also acts to stimulate research in this direction. The contents are based on a wide range of functional monomers and the contributions are written by eminent researchers. Specifically Renewable Polymers: Demonstrates the design, synthesis, properties and applications of plant oil-based polymers Presents an elaborate review of acid mediated polymerization techniques for the generation of green polymers Details the production of polyhydroxyalkanoates (PHA) from olive oil based wastewater Describes the use of atom transfer radical polymerization (ATRP) techniques Reviews the renewable polymers derived from transgenic crop plants Provides an overview of a range of biomass-based polymers Concludes with the recent efforts and approaches exploiting the natural materials in developing drug delivery systems.
Robin Hicks Stable Radicals. Fundamentals and Applied Aspects of Odd-Electron Compounds Robin Hicks Stable Radicals. Fundamentals and Applied Aspects of Odd-Electron Compounds Новинка

Robin Hicks Stable Radicals. Fundamentals and Applied Aspects of Odd-Electron Compounds

14546.53 руб. Найти похожее
Stable radicals – molecules with odd electrons which are sufficiently long lived to be studied or isolated using conventional techniques – have enjoyed a long history and are of current interest for a broad array of fundamental and applied reasons, for example to study and drive novel chemical reactions, in the development of rechargeable batteries or the study of free radical reactions in the body. In Stable Radicals: Fundamentals and Applied Aspects of Odd-Electron Compounds a team of international experts provide a broad-based overview of stable radicals, from the fundamental aspects of specific classes of stable neutral radicals to their wide range of applications including synthesis, materials science and chemical biology. Topics covered include: triphenylmethyl and related radicals polychlorinated triphenylmethyl radicals: towards multifunctional molecular materials phenalenyls, cyclopentadienyls, and other carbon-centered radicals the nitrogen oxides: persistent radicals and van der Waals complex dimers nitroxide radicals: properties, synthesis and applications the only stable organic sigma radicals: di-tert-alkyliminoxyls. delocalized radicals containing the hydrazyl [R2N-NR] unit metal-coordinated phenoxyl radicals stable radicals containing the thiazyl unit: synthesis, chemical, and materials properties stable radicals of the heavy p-block elements application of stable radicals as mediators in living-radical polymerization nitroxide-catalyzed alcohol oxidations in organic synthesis metal-nitroxide complexes: synthesis and magneto-structural correlations rechargeable batteries using robust but redox-active organic radicals spin labeling: a modern perspective functional in vivo EPR spectroscopy and imaging using nitroxides and trityl radicals biologically relevant chemistry of nitroxides Stable Free Radicals: Fundamentals and Applied Aspects of Odd-Electron Compounds is an essential guide to this fascinating area of chemistry for researchers and students working in organic and physical chemistry and materials science.
Gunter Mayer The Chemical Biology of Nucleic Acids Gunter Mayer The Chemical Biology of Nucleic Acids Новинка

Gunter Mayer The Chemical Biology of Nucleic Acids

12753.12 руб. Найти похожее
With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guided gene silencing nucleic acids based therapies innate immune recognition of nucleic acid light-responsive nucleic acids for the spatiotemporal control of biological processes DNA methylation frameworks for programming RNA devices RNA as a catalyst: The Diels-Alderase-Ribozyme evolving an understanding of RNA function by in vitro approaches the chemical biology of aptamers: synthesis and applications nucleic acids as detection tools bacterial riboswitch discovery and analysis The Chemical Biology of Nucleic Acids is an essential compendium of the synthesis of nucleic acids and their biological applications for bioorganic chemists, chemical biologists, medicinal chemists, cell biologists, and molecular biologists.
Greve Bent Evidence and Evaluation in Social Policy Greve Bent Evidence and Evaluation in Social Policy Новинка

Greve Bent Evidence and Evaluation in Social Policy

By examining the role of evidence in social policymaking and the extent of its influence, Evidence and Evaluation in Social Policy delves deeply into one of the central questions of the field for the last 20 years. Chronicles the trend towards evidence-based policy over the last decade Assesses the ways in which scarce resources can best be used for the best care, particularly in times of austerity Describes methodological innovation, the ways in which researchers and politicians are working together effectively, and suggestions for future improvement Covers topics such as the role of randomized controlled trials in shaping public policy; the pitfalls of evidence-based policy as a prescriptive ideal; the challenges of measuring public support for policy interventions; and the benefits of engaging local government decision-makers with evaluation research
Vikas Mittal In-situ Synthesis of Polymer Nanocomposites Vikas Mittal In-situ Synthesis of Polymer Nanocomposites Новинка

Vikas Mittal In-situ Synthesis of Polymer Nanocomposites

13417.35 руб. Найти похожее
The book series «Polymer Nano-, Micro- and Macrocomposites» provides complete and comprehensive information on all important aspects of polymer composite research and development, including, but not limited to synthesis, filler modification, modeling, characterization as well as application and commercialization issues. Each book focuses on a particular topic and gives a balanced in-depth overview of the respective subfi eld of polymer composite science and its relation to industrial applications. With the books the readers obtain dedicated resources with information relevant to their research, thereby helping to save time and money. In-situ intercalative polymerization in the presence of filler provides distinct advantages when compared to other nanocomposite synthesis techniques including the possibility to polymerize a large range of thermoplastic and thermosetting polymers, improved handling of gaseous or liquid monomers or high pressure polymerization and improved control of heat of polymerization. This volume aims to highlight these advantages of the generation of polymer nanocomposites with a large spectrum of polymer matrices. Following an overview of the synthesis methodologies, the text goes on to discuss the most relevant polymer materials, including polyamides, polyolefi nes, polyacrylates, polyethylenes, polyurethanes, polyesters and polyepoxides.
Quin Louis D. Fundamentals of Heterocyclic Chemistry. Importance in Nature and in the Synthesis of Pharmaceuticals Quin Louis D. Fundamentals of Heterocyclic Chemistry. Importance in Nature and in the Synthesis of Pharmaceuticals Новинка

Quin Louis D. Fundamentals of Heterocyclic Chemistry. Importance in Nature and in the Synthesis of Pharmaceuticals

Heterocyclic chemistry is of prime importance as a sub-discipline of Organic Chemistry, as millions of heterocyclic compounds are known with more being synthesized regularly Introduces students to heterocyclic chemistry and synthesis with practical examples of applied methodology Emphasizes natural product and pharmaceutical applications Provides graduate students and researchers in the pharmaceutical and related sciences with a background in the field Includes problem sets with several chapters
Robert Pardo The Evaluation and Optimization of Trading Strategies Robert Pardo The Evaluation and Optimization of Trading Strategies Новинка

Robert Pardo The Evaluation and Optimization of Trading Strategies

A newly expanded and updated edition of the trading classic, Design, Testing, and Optimization of Trading Systems Trading systems expert Robert Pardo is back, and in The Evaluation and Optimization of Trading Strategies, a thoroughly revised and updated edition of his classic text Design, Testing, and Optimization of Trading Systems, he reveals how he has perfected the programming and testing of trading systems using a successful battery of his own time-proven techniques. With this book, Pardo delivers important information to readers, from the design of workable trading strategies to measuring issues like profit and risk. Written in a straightforward and accessible style, this detailed guide presents traders with a way to develop and verify their trading strategy no matter what form they are currently using–stochastics, moving averages, chart patterns, RSI, or breakout methods. Whether a trader is seeking to enhance their profit or just getting started in testing, The Evaluation and Optimization of Trading Strategies offers practical instruction and expert advice on the development, evaluation, and application of winning mechanical trading systems.
Practical Program Evaluation: Assessing and Improving Planning, Implementation, and Effectiveness Practical Program Evaluation: Assessing and Improving Planning, Implementation, and Effectiveness Новинка

Practical Program Evaluation: Assessing and Improving Planning, Implementation, and Effectiveness

"Practical Program Evaluation: Assessing and Improving Planning, Implementation, and Effectiveness" introduces students to the real world of evaluation, focusing on issues that arise in professional practice. Author Huey T. Chen concentrates on the steps vital to program evaluation: systematically identifying stakeholder needs, selecting evaluation options best suited to particular needs and reconciling any necessary tradeoffs, and turning the decisions into action. Using illustrative examples from the field, the book details the methods and procedures involved in analyzing and identifying stakeholder expectations and selecting an evaluation strategy. The principles and strategies presented are reinforced with theoretical justification. This provides students and professional evaluators the knowledge and flexibility to design suitable evaluations and follow them through from start to finish.
Thomas Nugent C. Chiral Amine Synthesis. Methods, Developments and Applications Thomas Nugent C. Chiral Amine Synthesis. Methods, Developments and Applications Новинка

Thomas Nugent C. Chiral Amine Synthesis. Methods, Developments and Applications

16273.51 руб. Найти похожее
This first comprehensive presentation of this hot and important topic compiles the most up-to-date methods for chiral amine synthesis. The international list of authors reads like a «Who's Who» of the subject, providing a large array of highly practical information concentrated into the useful and essential methods. Following an introductory chapter devoted to helping readers quickly determine which strategies to choose for their investigation, this handbook and ready reference focuses on the examination of methods that are reliable and simultaneously efficient for the synthesis of structurally diverse aliphatic and aromatic chiral amines. Modern methods and applications found in (pharmaceutical) industry are also covered.
Antonietti Markus Chemical Synthesis and Applications of Graphene and Carbon Materials Antonietti Markus Chemical Synthesis and Applications of Graphene and Carbon Materials Новинка

Antonietti Markus Chemical Synthesis and Applications of Graphene and Carbon Materials

12620.28 руб. Найти похожее
This ready reference and handbook is unique in its focus on synthesis and the application of graphene and other carbon materials with an emphasis on chemistry aspects. To this extent, it deals with top-down and bottom-up approaches across the different length scales for graphene from polycyclic aromatic hydrocarbons to graphene nanoribbons and graphene sheets, as well as carbon materials from quantum dots, nanostructured particles, and fibers, right up to tubes, bulk structures, and much more besides. In so doing, it presents the best synthetic methods: pyrolysis, chemical vapor deposition, templating and surface-mediated synthesis, self-assembly, surface-grafting and modification. Edited by two excellent, experienced and highly renowned editors, both of whom are directors of Max Planck Institutes.
Alain Tressaud Functionalized Inorganic Fluorides. Synthesis, Characterization and Properties of Nanostructured Solids Alain Tressaud Functionalized Inorganic Fluorides. Synthesis, Characterization and Properties of Nanostructured Solids Новинка

Alain Tressaud Functionalized Inorganic Fluorides. Synthesis, Characterization and Properties of Nanostructured Solids

14878.64 руб. Найти похожее
Functionalized Inorganic Fluorides: Synthesis, Characterization & Properties of Nanostructured Solids covers several classes of nanostructured and functionalized inorganic fluorides, oxide-fluorides, and fluorinated oxides such as silica and alumina. Ranging from powders or glass-ceramics to thin layers and coatings, they have applications as more efficient and less aggressive catalysts, UV absorbers, planar optical waveguides, integrated lasers and optical amplifiers, luminescent materials, anti-reflective coatings and high Tc superconductors. With a focus on new types of solids, such as nanopowders, hybrids, mesoporous fluorides, and intercalation compounds, the book covers new synthesis routes; physical-chemical characterizations – including morphology, structure, spectroscopic and optical behaviour; detailed ab initio investigations and simulations; and -last but not least- potential applications.
Vikas Mittal High Performance Polymers and Engineering Plastics Vikas Mittal High Performance Polymers and Engineering Plastics Новинка

Vikas Mittal High Performance Polymers and Engineering Plastics

12952.39 руб. Найти похожее
This book describes advances in synthesis, processing, and technology of environmentally friendly polymers generated from renewable resources. With contents based on a wide range of functional monomers and contributions from eminent researchers, this volume demonstrates the design, synthesis, properties and applications of plant oil based polymers, presenting an elaborate review of acid mediated polymerization techniques for the generation of green polymers. Chemical engineers are provided with state-of-the-art information that acts to further progress research in this direction.
Armando Cordova Catalytic Asymmetric Conjugate Reactions Armando Cordova Catalytic Asymmetric Conjugate Reactions Новинка

Armando Cordova Catalytic Asymmetric Conjugate Reactions

14546.53 руб. Найти похожее
This unique and long-awaited handbook on this important topic in the hot field of stereoselective organic synthesis covers several types of nucleophiles. Top international authors deal with modern forms of achieving stereoselective conjugate additions based on the use of chiral auxiliaries or asymmetric catalysis, such as P-N ligands, organocatalysis, domino reactions, Lewis acid and base catalysis. There is also a discussion of the employment of enantioselective conjugate addition transformations in total synthesis of important molecules. With its reliable and previously unpublished experimental procedures, this is a true source of high quality information.
Liming Xiu Nanometer Frequency Synthesis Beyond the Phase-Locked Loop Liming Xiu Nanometer Frequency Synthesis Beyond the Phase-Locked Loop Новинка

Liming Xiu Nanometer Frequency Synthesis Beyond the Phase-Locked Loop

Introducing a new, pioneering approach to integrated circuit design Nanometer Frequency Synthesis Beyond Phase-Locked Loop introduces an innovative new way of looking at frequency that promises to open new frontiers in modern integrated circuit (IC) design. While most books on frequency synthesis deal with the phase-locked loop (PLL), this book focuses on the clock signal. It revisits the concept of frequency, solves longstanding problems in on-chip clock generation, and presents a new time-based information processing approach for future chip design. Beginning with the basics, the book explains how clock signal is used in electronic applications and outlines the shortcomings of conventional frequency synthesis techniques for dealing with clock generation problems. It introduces the breakthrough concept of Time-Average-Frequency, presents the Flying-Adder circuit architecture for the implementation of this approach, and reveals a new circuit device, the Digital-to-Frequency Converter (DFC). Lastly, it builds upon these three key components to explain the use of time rather than level to represent information in signal processing. Provocative, inspiring, and chock-full of ideas for future innovations, the book features: A new way of thinking about the fundamental concept of clock frequency A new circuit architecture for frequency synthesis: the Flying-Adder direct period synthesis A new electronic component: the Digital-to-Frequency Converter A new information processing approach: time-based vs. level-based Examples demonstrating the power of this technology to build better, cheaper, and faster systems Written with the intent of showing readers how to think outside the box, Nanometer Frequency Synthesis Beyond the Phase-Locked Loop is a must-have resource for IC design engineers and researchers as well as anyone who would like to be at the forefront of modern circuit design.
Talbot John Stephens' Detection and Evaluation of Adverse Drug Reactions. Principles and Practice Talbot John Stephens' Detection and Evaluation of Adverse Drug Reactions. Principles and Practice Новинка

Talbot John Stephens' Detection and Evaluation of Adverse Drug Reactions. Principles and Practice

26502.58 руб. Найти похожее
The detection and evaluation of adverse drug reactions is crucial for understanding the safety of medicines and for preventing harm in patients. Not only is it necessary to detect new adverse drug reactions, but the principles and practice of pharmacovigilance apply to the surveillance of a wide range of medicinal products. Stephens' Detection and Evaluation of Adverse Drug Reactions provides a comprehensive review of all aspects of adverse drug reactions throughout the life cycle of a medicine, from toxicology and clinical trials through to pharmacovigilance, risk management, and legal and regulatory requirements. It also covers the safety of biotherapeutics and vaccines and includes new chapters on pharmacogenetics, proactive risk management, societal considerations, and the safety of drugs used in oncology and herbal medicines. This sixth edition of the classic text on drug safety is an authoritative reference text for all those who work in pharmacovigilance or have an interest in adverse drug reactions, whether in regulatory authorities, pharmaceutical companies, or academia. Praise for previous editions "This book presents a comprehensive and wide-ranging overview of the science of pharmacovigilance. For those entering or already experienced in the pharmaceutical sciences, this is an essential work.” – from a review in E-STREAMS «…a key text in the area of pharmacovigilance…extensively referenced and well-written…a valuable resource…» – from a review in The Pharmaceutical Journal
Chattopadhyay Shital K. Heterocycles in Natural Product Synthesis Chattopadhyay Shital K. Heterocycles in Natural Product Synthesis Новинка

Chattopadhyay Shital K. Heterocycles in Natural Product Synthesis

15210.75 руб. Найти похожее
Filling a gap on the market, this handbook and ready reference is unique in its discussion of the usefulness of various heterocyclic systems in the synthesis of natural products. Clearly structured for easy access to the information, each chapter is devoted to a certain class of heterocycle, providing a tabular presentation of the natural products to be covered containing the particular heterocyclic ring system along with their biological profile, occurrence and most important physical properties, backed by the appropriate references. In addition, the application of the heterocyclic system to the synthesis of natural products ic covered in detail. Of great interest to organic, natural products, medicinal and biochemists, as well as those working in the pharmaceutical and agrochemical industry.
Albini Angelo Photochemically-Generated Intermediates in Synthesis Albini Angelo Photochemically-Generated Intermediates in Synthesis Новинка

Albini Angelo Photochemically-Generated Intermediates in Synthesis

Examines the latest applications of photochemistry to generate important intermediates Presenting the latest breakthroughs in the field of organic photochemistry, this book offers tested and proven photochemical approaches to synthesis, creating promising new possibilities and applications for photochemical reactions. It focuses on photoreactions involving an intermediate where mechanistic aspects control the course of the reaction and its synthetic value. Readers will discover new insights into the mechanisms and nature of photo-produced reactive intermediates for organic synthesis as well as the methods to generate them. Moreover, by focusing on highly efficient techniques for producing such species, the authors enable researchers to design and perform photoreactions within the framework of green, sustainable chemistry. Photochemically-Generated Intermediates in Synthesis begins with a discussion of the principles and practice of photo-generated intermediates. Next, the book explores: Photogeneration of carbon-centered radicals Photogeneration of heteroatom-centered radicals Photogeneration of biradicals and radical pairs Photochemical generation of radical ions Photogeneration of carbocations and carbanions Photogeneration of carbenes and nitrenes The book's final chapter is dedicated to the photochemical manipulation of intermediates. Each chapter includes key kinetic data for typical intermediates as well as detailed case examples, giving readers all the tools needed to perform their own photochemical reactions. Comparisons to non-photochemical methods are offered whenever possible. Photochemically-Generated Intermediates in Synthesis sets the stage for greater collaboration among photochemists and synthetic organic chemists, enabling these two research communities to fully leverage photochemistry in order to generate key intermediates needed for a broad range of synthetic reactions in organic chemistry.
Manfred Schlosser Organometallics in Synthesis, Third Manual Manfred Schlosser Organometallics in Synthesis, Third Manual Новинка

Manfred Schlosser Organometallics in Synthesis, Third Manual

WINNER of the 2013 PROSE Award in Chemistry & Physics This latest edition enables readers to master new classes of organometallic compounds and syntheses A popular resource used by synthetic organic chemists around the world, this book enables readers to conduct seamless synthetic reactions involving key organometallics. Each reaction is set forth in the book's acclaimed recipe-style format so that readers can easily replicate the results in their own labs. Moreover, each chapter has been written by a world leader in the field of organometallics in organic synthesis. These authors offer hands-on guidance and practical examples illustrating the preparation of organometallics and its application in organic synthesis. This Third Manual of Organometallics in Synthesis features completely new content and topics, with an eye towards providing researchers with the most useful and practical reference on the synthesis of organometallics. Organized into chapters by type of organometallic compound, the book covers: Organoalkali chemistry Organomagnesium and organozinc chemistry Organosilicon and relating organotin chemistry Organoiron chemistry Organopalladium chemistry Within each chapter, readers will find background information to learn more about the class of organometallics as well as mechanistic considerations. The authors thoroughly discuss the various methods of preparing the organometallic compounds presented in the book and outline their uses in synthetic reactions. In addition to current applications, the authors explore future research opportunities for each organometallic class. References at the end of each chapter enable readers to explore all the topics in greater depth. More and more industrial processes rely on organometallic chemistry. As a result, readers will find this book's step-by-step instructions essential in such fields as natural product synthesis, pharmaceuticals, fine chemicals, biotechnology, polymers, and materials science.
Evergreen Stephanie Data Visualization, Part 2. New Directions for Evaluation, Number 140 Evergreen Stephanie Data Visualization, Part 2. New Directions for Evaluation, Number 140 Новинка

Evergreen Stephanie Data Visualization, Part 2. New Directions for Evaluation, Number 140

This issue delivers concrete suggestions for optimally using data visualization in evaluation, as well as suggestions for best practices in data visualization design. It focuses on specific quantitative and qualitative data visualization approaches that include data dashboards, graphic recording, and geographic information systems (GIS). Readers will get a step-by-step process for designing an effective data dashboard system for programs and organizations, and various suggestions to improve their utility. The next section illustrates the role that graphic recording can play in helping programs and evaluators understand and communicate the mission and impact that an intervention is having in a democratic and culturally competent way. The GIS section provides specific examples of how mapped data can be used to understand program implementation and effectiveness, and the influence that the environment has on these outcomes. Discusses best practices that inform and shape our data visualization design choices Highlights the best use of each tool/approach Provides suggestions for effective practice Discuss the strengths and limitations of each approach in evaluation practice This is the 140th volume of the Jossey-Bass quarterly report series New Directions for Evaluation, an official publication of the American Evaluation Association.
Sisson Adam Handbook of Biodegradable Polymers. Isolation, Synthesis, Characterization and Applications Sisson Adam Handbook of Biodegradable Polymers. Isolation, Synthesis, Characterization and Applications Новинка

Sisson Adam Handbook of Biodegradable Polymers. Isolation, Synthesis, Characterization and Applications

14214.42 руб. Найти похожее
A comprehensive overview of biodegradable polymers, covering everything from synthesis, characterization, and degradation mechanisms while also introducing useful applications, such as drug delivery systems and biomaterial-based regenerative therapies. An introductory section deals with such fundamentals as basic chemical reactions during degradation, the complexity of biological environments and experimental methods for monitoring degradation processes. The result is a reliable reference source for those wanting to learn more about this important class of polymer materials, as well as scientists in the field seeking a deeper insight.
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Urban Remote Sensing is designed for upper level undergraduates, graduates, researchers and practitioners, and has a clear focus on the development of remote sensing technology for monitoring, synthesis and modeling in the urban environment. It covers four major areas: the use of high-resolution satellite imagery or alternative sources of image date (such as high-resolution SAR and LIDAR) for urban feature extraction; the development of improved image processing algorithms and techniques for deriving accurate and consistent information on urban attributes from remote sensor data; the development of analytical techniques and methods for deriving indicators of socioeconomic and environmental conditions that prevail within urban landscape; and the development of remote sensing and spatial analytical techniques for urban growth simulation and predictive modeling.
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Transition metals open up new opportunities for synthesis, because their means of bonding and their reaction mechanisms differ from those of the elements of the s and p blocks. In the last two decades the subject has mushroomed – established reactions are seeing both technical improvements and increasing numbers of applications, and new reactions are being developed. The practicality of the subject is demonstrated by the large number of publications coming from the process development laboratories of pharmaceutical companies, and its importance is underlined by the fact that three Nobel prizes have been awarded for discoveries in this field in the 21st Century already. Organic Synthesis Using Transition Metals, 2nd Edition considers the ways in which transition metals, as catalysts and reagents, can be used in organic synthesis, both for pharmaceutical compounds and for natural products. It concentrates on the bond-forming reactions that set transition metal chemistry apart from «classical» organic chemistry. Each chapter is extensively referenced and provides a convenient point of entry to the research literature. Topics covered include: introduction to transition metals in organic synthesis coupling reactions C-H activation carbonylative coupling reactions alkene and alkyne insertion reactions electrophilic alkene and alkyne complexes reactions of alkyne complexes carbene complexes h3- or p-allyl -allyl complexes diene, dienyl and arene complexes cycloaddition and cycloisomerisation reactions For this second edition the text has been extensively revised and expanded to reflect the significant improvements and advances in the field since the first edition, as well as the large number of new transition metal-catalysed processes that have come to prominence in the last 10 years – for example the extraordinary progress in coupling reactions using “designer” ligands, catalysis using gold complexes, new opportunities arising from metathesis chemistry, and C-H activation – without neglecting the well established chemistry of metals such as palladium. Organic Synthesis Using Transition Metals, 2nd Edition will find a place on the bookshelves of advanced undergraduates and postgraduates working in organic synthesis, catalysis, medicinal chemistry and drug discovery. It is also useful for practising researchers who want to refresh and enhance their knowledge of the field.
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One approach to organic synthesis is retrosynthetic analysis. With this approach chemists start with the structures of their target molecules and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. This “disconnection” approach to synthesis is now a fundamental part of every organic synthesis course. Workbook for Organic Synthesis: The Disconnection Approach, 2nd Edition This workbook provides a comprehensive graded set of problems to illustrate and develop the themes of each of the chapters in the textbook Organic Synthesis: The Disconnection Approach, 2nd Edition. Each problem is followed by a fully explained solution and discussion. The examples extend the student’s experience of the types of molecules being synthesised by organic chemists, and the strategies they employ to control their syntheses. By working through these examples students will develop their skills in analysing synthetic challenges, and build a toolkit of strategies for planning new syntheses. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. Together the workbook and textbook provide a complete course in retrosynthetic analysis. Organic Synthesis: The Disconnection Approach, 2nd Edition There are forty chapters in Organic Synthesis: The Disconnection Approach, 2nd Edition: those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specifically designed for difficult problems. In its second edition updated examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel, Organic Synthesis: Strategy and Control. Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry. Workbook for Organic Synthesis: The Disconnection Approach, 2nd edition, combined with the main textbook, provides a full course in retrosynthetic analysis for chemistry and biochemistry students, and a refresher course for organic chemists working in industry and academia.
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Посредством этого сайта магазина - каталога товаров мы очень легко осуществляем продажу synthesis and pharmacological evaluation of thiazolidinediones у одного из интернет-магазинов проверенных фирм. Определитесь с вашими предпочтениями один интернет-магазин, с лучшей ценой продукта. Прочитав рекомендации по продаже synthesis and pharmacological evaluation of thiazolidinediones легко охарактеризовать производителя как превосходную и доступную фирму.